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Drug Guide    A   Antispasmotic

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   Antispasmotic

Antispasmotic
Oral


This medication is used along with other medications to treat certain intestine problems (irritable bowel syndrome, enterocolitis). This medication contains several medications, phenobarbital and belladonna alkaloids (hyoscyamine, atropine, scopolamine). This medication belongs to a class of drugs known as anticholinergic/antispasmodic drugs. It works by decreasing intestine cramping and calming the nerves.



 
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 Antispasmotic images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions



Antispasmotic

Uses
This medication is used along with other medications to treat certain intestine problems (irritable bowel syndrome, enterocolitis). This medication contains several medications, phenobarbital and belladonna alkaloids (hyoscyamine, atropine, scopolamine). This medication belongs to a class of drugs known as anticholinergic/antispasmodic drugs. It works by decreasing intestine cramping and calming the nerves.
Notes
  • Do not share this medication with others.Keep all medical appointments so that your progress can be monitored or you can be checked for side effects.
  • Consult your doctor for more details.

Storage
  • Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: headache, restlessness, unusual behavior, excitability, nausea, vomiting, blurred vision, widened pupils, hot and dry skin, dizziness, dry mouth, difficulty swallowing.

How To Use
  • Take this medication by mouth, exactly as prescribed by your doctor.
  • Follow your doctor's instructions carefully on taking this drug with or without food.
  • If you are taking the extended-release tablets, take them usually every 8 to 12 hours.
  • If you are taking the regular-release tablets or elixir, take them usually 3 to 4 times daily.
  • Children may be prescribed the elixir every 4 to 6 hours.Dosage is based on your medical condition and response to treatment.
  • Dosage for children is also based on body weight.
  • Your doctor may adjust your dosage to control symptoms and decrease side effects.Use this medication regularly to get the most benefit from it.
  • To help you remember, take it at the same times each day.This medication may cause dependence, especially if it has been used regularly for an extended time or if it has been used in higher doses.
  • In such cases, withdrawal reactions (e.g., anxiousness, muscle twitching, shakiness, dizziness, worsening weakness, nausea, vomiting) may occur if you suddenly stop this drug.
  • Withdrawal from the phenobarbital can be severe and include seizures and (rarely) death.
  • To prevent withdrawal reactions when stopping extended, high-dose, regular treatment with this drug, gradually reduce the dosage as directed.
  • Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.Rarely, abnormal drug-seeking behavior (addiction) is possible with this medication.
  • Do not increase your dose, take it more frequently, or use it for a longer time than prescribed.
  • Properly stop the medication when so directed.
  • Tell your doctor if your condition persists or worsens at any time while taking this medication.

Side Effects
  • Drowsiness, dizziness, blurred vision, dry mouth, dry eyes, constipation, or fast heartbeat may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.To relieve dry mouth, suck on hard candy or ice chips, chew gum, drink water, or use a saliva substitute.To prevent constipation, maintain a diet adequate in fiber, and drink plenty of water.
  • If you become constipated while using this drug, consult your pharmacist for help in selecting a laxative (e.g., stimulant-type with stool softener).Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/irregular heartbeat, weakness, headache, mental/mood changes (e.g., nervousness, confusion, agitation, excitement), loss of taste, nausea, vomiting, decreased sweating, reduced tolerance of heat/strenuous exercise, problems starting the flow of urine, decreased sexual ability/interest.For more details about heat tolerance, see Precautions section.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking belladonna alkaloids with phenobarbital, tell your doctor or pharmacist if you are allergic to hyoscyamine, atropine, scopolamine, or phenobarbital; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: glaucoma, urine blockage due to enlarged prostate, blockage or narrowing in the stomach/intestines, severe slowing or stoppage of the intestines (e.g., intestinal atony, paralytic ileus), any condition that causes immobility (e.g., being bedridden), severe bleeding, a certain severe form of intestinal disease (ulcerative colitis), a certain muscle disease (myasthenia gravis), severe bleeding with fainting, hiatal hernia with heartburn, a certain blood/liver problem (acute intermittent porphyria), restlessness or excitement due to past use of phenobarbital.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, kidney problems, heart disease (e.g., angina, heart rhythm problems, previous heart attack, chronic heart failure), high blood pressure, sleep apnea, nerve problems causing slowing of the intestines (autonomic neuropathy), mental/mood disorders (e.g., toxic psychosis, depression), stomach ulcer.This drug may make you dizzy or drowsy or cause blurred vision.
  • Use caution while driving, using machinery, or doing any activity that requires alertness and clear vision.
  • Avoid alcoholic beverages because they may increase the risk of these side effects.When this medication is taken in hot weather, a certain serious condition (heat prostration) may occur due to decreased sweating.
  • Drink plenty of fluids and dress lightly while in hot weather or when exercising.
  • Check carefully for signs of decreased sweating.
  • If this occurs, promptly seek cooler or air-conditioned shelter and/or stop exercising.
  • Seek immediate medical attention if your body temperature is above normal or if you have mental/mood changes, headache, or dizziness.If you wear contact lenses and have dry eyes, you may need to use appropriate lubricating drops.
  • Consult your doctor or pharmacist.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially drowsiness and urination problems.During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.
  • Birth control pills may not be effective if taken with this medication (see also Drug Interactions section).
  • Discuss reliable forms of birth control with your doctor.
  • If you become pregnant while taking this medication, tell your doctor immediately.This medication passes into breast milk and may have undesirable effects on a nursing infant.
  • Breast milk production may also be decreased by this medication.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: sodium oxybate, pramlinitide, solid potassium chloride supplements taken by mouth, delavirdine, darunavir, voriconazole.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting belladonna alkaloids with phenobarbital.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: warfarin, estrogens, corticosteroids (e.g., prednisone, dexamethasone), quinidine, felodipine, metronidazole, doxycycline, griseofulvin, phenytoin, valproic acid, cyclosporine, sunitinib, erlotinib, telithromycin, certain beta blockers (acebutolol, betaxolol, carteolol, metoprolol, propranolol), exemestane, theophylline, MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine).Before using this medication, tell your doctor or pharmacist if you use any other prescription and nonprescription products that cause drowsiness such as certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants (e.g., methocarbamol), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that have similar side effects to this medication (e.g., drowsiness, dry eyes, dry mouth, constipation, urination problems).
  • Ask your pharmacist about using those products safely.This medication may decrease the effectiveness of combination-type birth control pills or patches/rings.
  • This can result in pregnancy.
  • You may need to use an additional form of reliable birth control while using this medication.
  • Consult your doctor or pharmacist for details.
  • (See also Precautions section.)

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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