Anti-Inhibitor Coagulant CmplxIV - Drug Information and Side Effects on Drug3k.com


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Overview

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How To Use

Side Effects

Precautions

Missed Dose

Drug Interactions

Anti-Inhibitor Coagulant Cmplx

Uses
This medication is used to treat patients with certain blood-clotting conditions (hemophilia with inhibitors) before surgery or during an attack of bleeding. People with these blood-clotting conditions have certain abnormal substances (inhibitors) that make it hard for blood to thicken (clot). Therefore, these people may bleed longer after surgery/injury or may bleed suddenly (often in the joints/muscles). This medication stops these inhibitors and allows the blood to clot so that you can stop bleeding. This medication also contains several different substances (factors) needed for the blood to clot.This medication should not be used to treat other types of factor deficiencies (e.g., factors II, VII, VIII, IX, X).
Notes

Laboratory and/or medical tests (e.g., fibrinogen levels) may be performed periodically to monitor your progress or check for side effects.
Consult your doctor for more details.

Storage

Before mixing, refrigerate the dry powder and mixing solution between 36-46 degrees F (2-8 degrees C).
Do not freeze.
The unmixed vials may be stored for up to 6 months at room temperature at or below 77 degrees F (25 degrees C).
Do not return the product to the refrigerator after storing at room temperature.
Write the date the product was removed from the refrigerator on the product and discard after 6 months or after the expiration date on the label, whichever is sooner.Once this medication has been mixed, use it immediately.
Discard any unused solution 3 hours after mixing.
Do not refrigerate for later use.

How To Use

This medication is given slowly by injection into a vein by a health care professional.
Health care professionals must follow all the manufacturer's instructions for properly mixing and giving this drug.
Before mixing, warm the medication to room temperature.
Do not refrigerate the solution after mixing.
If you have any questions about using this medication properly, consult your doctor or pharmacist.Dosage is based on your medical condition (e.g., amount and location of bleeding), weight, and response to treatment.Tell your doctor if your condition persists or worsens.

Side Effects

Pain/swelling at injection site, fever, chills, dizziness, or nausea may occur.
If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: new or worsening bleeding/bruising, signs of anemia (e.g., tiredness, low energy, pale skin, shortness of breath), fainting, fast heartbeat, lightheadedness, rash/joint pain (up to 2 weeks after using drug).This medication may rarely cause serious blood clots.
Seek immediate medical attention if you notice any of the following rare but very serious side effects: painful/difficult breathing, cough, bluish fingers, pain/redness/swelling of arms/legs, calf pain/swelling that is warm to the touch, chest/jaw/left arm pain, sudden vision changes, confusion, slurred speech, weakness on one side of the body, sudden severe headache.A very serious allergic reaction to this drug is rare.
However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to latex; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have: certain clotting disorders (disseminated intravascular coagulation-DIC, fibrinolysis).Before using this medication, tell your doctor or pharmacist your medical history.This medication is made from human blood.
Even though donors are carefully screened and this medication goes through a special manufacturing process, there is a very small chance that you may get infections from the medication (e.g., virus infections such as hepatitis).
It is recommended that you get the appropriate vaccinations (e.g., for hepatitis A and B) and that people giving this medication handle the medication with special caution.
Consult your doctor for more details.
Tell your doctor immediately if you develop any signs of hepatitis/another infection, including fever, persistent sore throat, unusual tiredness, persistent nausea/vomiting, yellowing eyes/skin, dark urine.During pregnancy, this medication should be used only when clearly needed.
Discuss the risks and benefits with your doctor.It is not known whether this medication passes into breast milk.
Consult your doctor before breast-feeding.

Missed Dose

Not applicable.

Drug Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs that help with clotting (e.g., aminocaproic acid, tranexamic acid).

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.