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Amitriptyline/chlordiazepoxide Limbitrol Uses Amitriptyline is an antidepressant used to treat depression. Chlordiazepoxide is an anti-anxiety medication used to relieve nervousness and tension. This combination medication works faster and has less side effects than either medication alone. Storage Store at room temperature away from sunlight and moisture. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include drowsiness, confusion, fast heartbeat, lightheadedness, and dilated pupils. How To Use Take Amitriptyline/chlordiazepoxide with food or milk if stomach upset occurs. Take Amitriptyline/chlordiazepoxide exactly as prescribed. Do not increase your dose or take it more often than prescribed. Do not stop taking Amitriptyline/chlordiazepoxide without your doctor s approval. Nausea, headache or fatigue can occur if Amitriptyline/chlordiazepoxide is suddenly stopped. Your dose may have to be gradually decreased if you have been taking it for some time. Side Effects Amitriptyline/chlordiazepoxide may cause drowsiness, dizziness, increased sun sensitivity or blurred vision. Other side effects may include stomach upset, headache, lightheadedness, confusion, depression, impaired coordination, trembling, weakness, memory loss, hangover effect (grogginess), dreaming or nightmares, loss of appetite, dry mouth, anxiety, restlessness or sweating. If these effects persist or worsen, notify your doctor promptly. Notify your doctor if you develop: chest pain, rapid or irregular heartbeat, vision changes, difficulty urinating, yellowing of the eyes or skin, uncoordinated movements, fainting, ringing in the ears. In the unlikely event you have an allergic reaction to Amitriptyline/chlordiazepoxide, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before using Amitriptyline/chlordiazepoxide tell your doctor your medical history, especially of: glaucoma, prostate problems, decreased urine output, thyroid disease, breathing problems, seizure problems, alcohol use, heart disease, mental/emotional problems, liver or kidney disease, drug allergies. Caution is advised when performing tasks requiring alertness (e.g., driving). Amitriptyline/chlordiazepoxide can increase sensitivity to sunlight. Avoid prolonged sun exposure. Wear a sunscreen and protective clothing. Limit alcohol while taking this to avoid excessive drowsiness. Caution is advised when using Amitriptyline/chlordiazepoxide in the elderly, because they may be more sensitive to the effects of Amitriptyline/chlordiazepoxide (e.g., confusion may occur or worsen). Amitriptyline/chlordiazepoxide is not recommended for use during pregnancy. Discuss the risks and benefits with your doctor. Amitriptyline/chlordiazepoxide is excreted into breast milk and may have an effect on the nursing infant. Consult your doctor before breast-feeding. Missed Dose Do not double dose if missed. Skip missed dose and resume your regular dosing schedule. Drug Interactions Inform your doctor about all Amitriptyline/chlordiazepoxides you use (both prescription and nonprescription), especially if you take other medicines that make you sleepy such as: narcotic pain relievers (e.g., codeine), MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), cimetidine, anti-thyroid medicine, SSRI antidepressants (e.g., fluoxetine, fluvoxamine), St John s wort. Do not start or stop any medicine without doctor or pharmacist approval.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.