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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Alefacept Uses Treats plaque psoriasis. This medicine is an immune suppressant (it slows down the immune system). How To Use APPEARANCE: Injectable, Injectable. Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles or through a needle placed in one of your veins. A nurse or other trained health professional will give you this medicine. This medicine is usually given once a week for 12 weeks. Some people might need to have another 12-week treatment. You must wait at least 12 weeks between each set of 12-week treatments. If you have questions, talk with your doctor. You may not see improvement in your skin right away. Your psoriasis may continue to get better even after you have stopped using this medicine. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Dark-colored urine or pale stools. Fever. Ongoing nausea, vomiting, loss of appetite, pain in your upper stomach. Severe chills, headache, muscle pain, and sinus (face and forehead) pain or pressure. Unusual bleeding or bruising. Unusual changes in your health. Yellowing of your skin or the whites of your eyes. Precautions You should not use this medicine if you have had an allergic reaction to alefacept, or if you have HIV or AIDS. Missed Dose Call your doctor, pharmacist, or treatment clinic for instructions. Drug Interactions Make sure your doctor knows if you are pregnant or breastfeeding. This medicine affects your immune system. This means you may get infections more easily. Avoid people who are sick or have infections. Make sure your doctor knows if you have any kind of infection before you start using this medicine. Also tell your doctor if you had an infection that would not go away or kept coming back. Call your doctor if you think you have an infection while using this medicine. A small number of people who have used this medicine have developed cancer. This is rare. Most of the cases were skin cancer. Make sure your doctor knows if you have had cancer before. Talk about this risk with your doctor, especially if you might have other risk factors. Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments. For women: Tell your doctor if you become pregnant while using this medicine or within 8 weeks after you stop using this medicine. This medicine is not known to cause problems with pregnancy, but your doctor might want you to enroll in a Pregnancy Registry.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.