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Estradiol/norethindrone images:

Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Estradiol/norethindrone Activella Uses Treats symptoms of menopause, including hot flashes, night sweats, and vaginal dryness and irritation. Estradiol is a type of estrogen. Norethindrone is a type of progestin. Storage Store at room temperature in a closed container, away from heat, moisture, and direct light. Keep this and all medicine out of the reach of children. How To Use APPEARANCE: Tablet. Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine sometimes comes in a special dispenser pack with a calendar reminder dial. To use this dispenser, first turn the inner disc so the current day of the week is lined up with the plastic tab. Pull the plastic tab up and break if off. Tip out the first tablet. To get the next tablet out (on the next day), turn the outer transparent dial one space clockwise as shown by the arrow. The transparent dial can be turned only after the tablet in the opening has been removed. This will help you to remember to take one tablet every day. Side Effects Call your doctor right away if you notice any of these side effects: Moderate to heavy vaginal bleeding Pelvic pain, discomfort, aching, or heaviness Sudden chest pain, trouble breathing, or coughing up blood Sudden severe headache, dizziness, change in speech, or weakness Sudden vision problems, including complete or partial loss of vision or double vision, or protruding eyeballs Swelling or pain in leg Yellow eyes or skin Precautions You should not use this medicine if you have had an allergic reaction to estradiol or norethindrone or if you are or may be pregnant. You should not use this medicine if you have blood clotting problems, liver disease, unexplained vaginal bleeding, or if you have or suspect you have certain types of cancer (including breast or endometrial cancer). Also, you should not use this medicine if you have a history of stroke or certain types of cancer (especially breast cancer). Missed Dose Use your medicine as soon as possible unless it is almost time for your next dose. Skip the missed dose if it is almost time for your next regular dose. Do not use two doses at the same time. Drug Interactions This medicine can cause severe birth defects in an unborn baby. Do not use this medicine while you are pregnant. If you are breastfeeding, talk to your doctor before using this medicine. Make sure your doctor knows if you have heart disease, circulation problems, diabetes, asthma, epilepsy, migraine headaches, or kidney problems. Also make sure your doctor knows if you feel depressed or have a history of depression. This medicine is intended to be used only by women who have an intact uterus (womb). Tell your doctor if you have had a hysterectomy (had your uterus removed). You may have irregular vaginal bleeding or spotting when you first start using this medicine. This is normal and should decrease over time. You should have regular check-ups with your doctor while you are using this medicine (usually every 6 to 12 months). This medicine may increase your risk for developing breast cancer or cancer of the uterus, especially with long-term use or large doses. Be sure to discuss this with your doctor. You can help combat breast cancer by doing regular breast self-exams (at any age) and having regular mammograms (if you are over 40). Ask your doctor if you do not know how to do a breast self-exam. Be sure you understand all the advantages and disadvantages of treatment with this medicine. Estrogen taken alone (without the progestin) has been know to cause endometrial cancer and heart, blood pressure, gallbladder, and circulation problems. Discuss this with your doctor.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.