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USES: This medication is an enzyme which works to break up and dissolve blood clots which can block arteries. It is used in the treatment of pulmonary embolism or blood clots. It may also be used to clear blood clots from catheters.
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Abbokinase
Uses
This medication is an enzyme which works to break up and dissolve blood clots which can block arteries. It is used in the treatment of pulmonary embolism or blood clots. It may also be used to clear blood clots from catheters.
Notes
- Laboratory tests will be done frequently while using this medication to monitor its effects and to prevent side effects.
Storage
- Store powder vial in refrigerator at 36-46 degrees F (2 to 8 degrees C).
- Reconstituted solution should be used immediately after reconstituting.
- Discard any unused portion.
Photos
How To Use
- HOW TO USE THIS MEDICATION: This medication is given by injection by a health care professional.
- It is important this medication be used as prescribed.
- It is most effective when administered as soon as possible after symptoms appear (e.g., within 6 hours of onset of chest pain).
Side Effects
- Dizziness or mild fever may occur.
- If any of these effects continue or become bothersome, inform your doctor.
- Notify your doctor if you experience easy bruising or bleeding, a skin rash, breathing trouble, a rapid or abnormal heartbeat or chest pain while using this medication.
- It can also cause nerve damage.
- Immediately report any signs of bleeding to your doctor.
- If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Tell your doctor if you have any pre-existing bleeding disorders, high blood pressure, endocarditis, recent biopsy or surgery, recent injury or any allergies.
- Use extra caution to avoid injury and trauma (e.g., carefully brushing teeth) while using this medication due to the increased risk of bleeding.
- Consult your doctor regarding the possible risk that this drug contains infectious material.
- This medication should be used only if clearly needed during pregnancy.
- Discuss the risks and benefits with your doctor.
- It is not known if this medication appears in breast milk.
- Consult your doctor before breast-feeding.
Missed Dose
- Continued dosing is usually not necessary for this medication.
Drug Interactions
- Tell your doctor of any over-the-counter or prescription medication you may take including any blood thinners, NSAID or aspirin.
- Drugs that can reverse effects of urokinase include aminocaproic acid, aprotinin and tranexamic acid.
- Do not start or stop any medicine without doctor or pharmacist approval.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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